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REAL CHEM Research

Built on Learning Science. Proven in Real Classrooms

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Large Gains in Gateway Chemistry

6.9% pt

Introductory Course Gains on Final Exam

14.5% pt

Advanced Course Gains on Midterm Exam

Outperforms

National

Benchmarks

American Chemical
Society (ACS)
Exam (MtSAC)

Using Data to Improve Chemistry Education

Built on Evidence. Improved by Data.

These feedback loops extend beyond simple tracking of student interactions. REAL CHEM aligns learning outcomes with course activities, enabling real-time insight into students’ understanding and areas of difficulty. This approach generates meaningful information for students, instructors, course designers, and researchers, supporting more informed decisions about teaching and learning.
REAL CHEM Feedback Loops — atomic system diagram Student Learning Data sits at the nucleus. Four orbiting actors exchange data and feedback in a continuous loop: Instructors (top) adapt teaching based on data; Course Designers (right) iterate course content and structure; Learning Science (bottom) refines the system through research; Student Performance (left) reflects and informs learning progress. Solid teal lines carry student signals outward; dashed gray lines carry refinements inward; curved arrows show the continuous improvement loop. STUDENT LEARNING DATA Instructors — teaching adapts based on data. INSTRUCTORS Course Designers — content and structure evolve. COURSE DESIGNERS Learning Science — research refines the system. LEARNING SCIENCE Student Performance — outcomes reflect and inform learning progress. STUDENT PERFORMANCE

The Research

Papers, conference proceedings, and posters from the REAL CHEM team and collaborators.

2026
CASE STUDY

Large Gains in Gateway Chemistry: REAL CHEM Enables Strong Gains When Combined with a Retake-Based Pedagogical Model

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CONFERENCE PROCEEDINGS

REAL CHEM Action Research Through the LearnLab Summer School.

Henderson, J. B., Bass, S. M., Dwyer, R. P., Larson, K., Mead, C., Stein, A., & Yaron, D. J. (2026). REAL CHEM Action Research Through the LearnLab Summer School. In Craig, S. D., Arner, T., & McNamara, D. S. (Eds.), Proceedings of LERN 2026.

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CONFERENCE PROCEEDINGS

Designing for Student Engagement with AI in Courseware

Stein, A., Ciou, S. T., Cui, T., Larson, K., Lee, L., Li, S., … & Yaron, D. J. (2026). Designing for Student Engagement with AI in Courseware: Lessons from Iterative Improvements to DOT in REAL CHEM. Proceedings of LERN 2026.

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POSTER

How Students Really Use Courseware: Visualizing Student Pathways in Integrated Chemistry Courseware

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POSTER

Keeping Chemistry Relevant: Tracking Student Sentiment in REAL CHEM

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POSTER

Reasoning LLMs are Competent Courseware Reviewers

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POSTER

Not All Practice is Equal: Learning Across Activity Types in Chemistry Courseware

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POSTER

DOT as an embedded AI learning partner in REAL CHEM

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POSTER

Mastery Learning in Large-Enrollment General Chemistry

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2025
JOURNAL ARTICLE

The promise of mastery-based testing for promoting student engagement, self-regulated learning, and performance in gateway STEM courses

Asher, M. W., Hartman, J. D., Blaser, M., Eichler, J. F., & Carvalho, P. F. (2025). The promise of mastery-based testing for promoting student engagement, self-regulated learning, and performance in gateway STEM courses. Computers & Education, 237, 105387.

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JOURNAL ARTICLE

Mathematics matters or maybe not: An astonishing independence between mathematics and the rate of learning in general chemistry

Koedinger, K. R., Blaser, M., McLaughlin, E. A., Cheng, H., & Yaron, D. J. (2025). Mathematics matters or maybe not: An astonishing independence between mathematics and the rate of learning in general chemistry. JACS Au, 5(3), 1268-1278.

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POSTER

Impact of Semester Timing on Student Outcomes in the First Course of a General Chemistry Sequence

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2024
JOURNAL ARTICLE

Implementing mastery grading in large enrollment general chemistry: improving outcomes and reducing equity gaps

Hartman, J. D., & Eichler, J. F. (2024). Implementing mastery grading in large enrollment general chemistry: improving outcomes and reducing equity gaps. Education Sciences, 14(11), 1224.

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FACULTY VOICE

Faculty as Research Partners

We collaborate with general chemistry instructors who want to study their classrooms.
Whether you're improving your course or running an IRB-approved study, REAL CHEM's data and team can support you.

“I’m really excited to continue with this community of practice and to take part in whatever comes next, like Community of Practice Convening this summer at BCCE. The digital collaboration has been great, but there’s nothing like being in the same room—you can see just how much gets accomplished in a short time. It’s been a truly great experience.”

Dr. Sarah Bass
University of Maryland, Baltimore County

“The research collaboration has been an incredibly rewarding experience—there’s something powerful about the shared accountability, expertise, and excitement. The foundation we built during last year’s Community of Practice Convening has carried forward into multiple ongoing projects, and we’re now getting close to producing publishable work from at least a couple of them.”

Dr. Josh Hartman
University of California, Riverside
Join Our Research Community

CONTENTS: REAL CHEM II

Cover of Real Chem II: Atomic Foundations of the Real World.
01

Chemical Kinetics

  • Reaction Rates
  • Rate Laws
  • Reaction Mechanisms
  • Exploration: Catalyst in the Clouds
02

Chemical Equilibrium

  • Concepts of Chemical Equilibrium 
  • Le Châtelier’s Principle 
  • Equilibrium Calculations
  • Exploration: Let’s Get the Lead Out!
03

Acids and Bases

  • Defining and Measuring Acids and Bases
  • Strong and Weak Acids and Bases
  • Exploration: Proton Power! pH and Protein Structure
04

Applications of Aqueous Equilibrium

  • Buffers 
  • Titrations
  • Solubility and Complex Ion Equilibria
05

Thermodynamics and Energy → What Drives a Reaction?

  • Introduction to Thermodynamics
  • The Second Law of Thermodynamics
  • Free Energy 
06

Electrochemistry

  • Foundational Concepts of Electrochemistry
  • Galvanic Cells 
  • Other Applications of Electrochemistry
07

Nuclear Chemistry

  • Nuclear Reactions and Equations
  • Applications of Nuclear Chemistry
08

Transition Metals and Coordination Chemistry

  • Occurrence, Preparation, and Properties of Transition Metals
  • Coordination Chemistry of Transition Metals
  • Spectroscopic and Magnetic Properties of Coordination Compounds
  • Exploration: Dazzling d-Orbitals
09

Appendix (REAL CHEM II)

  • Page: Specific Heats of Common Substances
  • Page: Solution for Large K
  • Page: Solution for Small K
  • Page: Ka Values of Common Weak Acids
  • Page: Kb Values of Common Weak Bases
  • Page: Solubility Products
  • Page: Titration
  • Page: Acid-Base Chemistry of Butterfly Tea and the Ocean
  • Page: Formation Constants for Complex Ions
  • Page: Standard Reduction Potentials
  • Page: Thermodynamic Properties
10

Appendix : PhET Simulations (REAL CHEM II)

  • Page: Gas Properties PhET Simulation
  • Page: Reactions and Rates PhET Simulation
  • Page: Acid-Base Solutions Introduction PhET Simulation
  • Page: pH Scale PhET Simulation
  • Page: Concentration PhET Simulation
  • Page: Salts and Solubility PhET Simulation
  • Page: Build a Nucleus PhET Simulation
  • Page: Radioactive Dating Game PhET Simulation
11

Glossary (REAL CHEM II)

  • Glossary (REAL CHEM II)
12

Instructor only resources (REAL CHEM II)

  • Page: In-class slide decks
  • Page: In-Class Active Learning Activities
  • Page: Learning objectives by module REAL CHEM II
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CONTENTS: REAL CHEM I

Real Chem course cover with ASU and Carnegie Mellon logos.
01

Unveiling the Power of Matter and Energy

  • Basic Concepts of Matter and Energy
  • Measurements
02

Unit 2: Atoms, Molecules and Ions

  • Atomic Theory and the Periodic Table
  • Compounds and Chemical Formulas
  • Exploration: Do you really want to drink that? The elements of water.
03

Electronic Structure and Periodic Properties

  • Electromagnetic Energy and the Bohr Model of the Atom
  • Quantum Theory
  • Periodic Properties
  • Exploration: What’s the World Made Of? Unlocking Secrets with Spectroscopy
04

Chemical Bonding and Molecular Geometry

  • Ionic and Covalent Bonding
  • Lewis Structures
  • Molecular Structure and Polarity
  • Advanced Theories of Covalent Bonding
  • Exploration: Decoding the Mystery of Greenhouse Molecules
05

Composition
of Substances

  • Mole Calculations
  • Aqueous Solutions
  • Exploration: Is the Town Toxic? Quantifying Concentrations of Lead.
06

Reactions and
Stoichiometry

  • Chemical Reactions and Equations
  • Chemical Reactions Stoichiometry
  • Exploration: Driving Down Greenhouse Emissions
07

Gases

  • Gas Laws
  • Stoichiometry of Gases
  • The Kinetic-Molecular Theory
08

Thermochemistry

  • Introduction to Energy
  • Calorimetry
  • Enthalpy
  • Exploration: What’s Our Next Big Energy Source?
09

Liquids and Solids

  • Intermolecular Forces
  • Phase Changes
  • The Solid State of Matter
10

Solutions

  • Solubility
  • Colligative Properties
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